August: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily.


Aug 1:

Yaffe, Michael B. “Reproducibility in science.” Sci. Signal. 8, no. 371 (2015): eg5-eg5.

Aug 2:

Naegle, Kristen, Nancy R. Gough, and Michael B. Yaffe. “Criteria for biological reproducibility: what does” n” mean?.Science signaling 8, no. 371 (2015): fs7.

Aug 3:

Parnas, Oren, Marko Jovanovic, Thomas M. Eisenhaure, Rebecca H. Herbst, Atray Dixit, Chun Jimmie Ye, Dariusz Przybylski et al. “A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks.” Cell 162, no. 3 (2015): 675-686.

Aug 4:

Evers, Bastiaan, Katarzyna Jastrzebski, Jeroen PM Heijmans, Wipawadee Grernrum, Roderick L. Beijersbergen, and Rene Bernards. “CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes.Nature biotechnology (2016).

Aug 5:

Housden, Benjamin E., and Norbert Perrimon. “Comparing CRISPR and RNAi-based screening technologies.Nature Biotechnology 34, no. 6 (2016): 621-623.

Aug 6:

Qi, Xiaolong, Jiwei Zhang, Yongzhao Zhao, Tao Chen, Yi Xiang, Jialiang Hui, Danxian Cai et al. “The applications of CRISPR screen in functional genomics.” Briefings in Functional Genomics (2016): elw020.

Aug 7:

Vickers, Claudia E. “The minimal genome comes of age.” Nature Biotechnology 34, no. 6 (2016): 623-624.

Aug 8:

Nam, Jae-Yong, Nayoung KD Kim, Sang Cheol Kim, Je-Gun Joung, Ruibin Xi, Semin Lee, Peter J. Park, and Woong-Yang Park. “Evaluation of somatic copy number estimation tools for whole-exome sequencing data.Briefings in bioinformatics 17, no. 2 (2016): 185-192.

Aug 9:

Belkadi, Aziz, Alexandre Bolze, Yuval Itan, Aurelie Cobat, Quentin B. Vincent, Alexander Antipenko, Lei Shang, Bertrand Boisson, Jean-Laurent Casanova, and Laurent Abel. “Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants.Proceedings of the National Academy of Sciences 112, no. 17 (2015): 5473-5478.

Aug 10:

Law, Charity W., Monther Alhamdoosh, Shian Su, Gordon K. Smyth, and Matthew E. Ritchie. “RNA-seq analysis is easy as 1-2-3 with limma, Glimma and edgeR.F1000Research 5 (2016).

Aug 11:

Schurch, Nicholas J., Pietá Schofield, Marek Gierliński, Christian Cole, Alexander Sherstnev, Vijender Singh, Nicola Wrobel et al. “How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?.” RNA 22, no. 6 (2016): 839-851.

Aug 12:

Delconte, Rebecca B., Tatiana B. Kolesnik, Laura F. Dagley, Jai Rautela, Wei Shi, Eva M. Putz, Kimberley Stannard et al. “CIS is a potent checkpoint in NK cell-mediated tumor immunity.Nature immunology (2016).

Aug 13:

Gamon, L. F., J. M. White, and U. Wille. “Oxidative damage of aromatic dipeptides by the environmental oxidants NO 2˙ and O 3.Organic & biomolecular chemistry 12, no. 41 (2014): 8280-8287.

Aug 14:

Cerami, Ethan, Jianjiong Gao, Ugur Dogrusoz, Benjamin E. Gross, Selcuk Onur Sumer, Bülent Arman Aksoy, Anders Jacobsen et al. “The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.Cancer discovery 2, no. 5 (2012): 401-404.

Aug 15:

Pham, Thu-Hang, Julia Minderjahn, Christian Schmidl, Helen Hoffmeister, Sandra Schmidhofer, Wei Chen, Gernot Längst, Christopher Benner, and Michael Rehli. “Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU. 1.Nucleic acids research (2013): gkt355.

Aug 16:

Nakamura, Tetsuya, Andrew R. Gehrke, Justin Lemberg, Julie Szymaszek, and Neil H. Shubin. “Digits and fin rays share common developmental histories.” Nature (2016).

Aug 17:

de Graaf, Carolyn A., Jarny Choi, Tracey M. Baldwin, Jessica E. Bolden, Kirsten A. Fairfax, Aaron J. Robinson, Christine Biben et al. “Haemopedia: An Expression Atlas of Murine Hematopoietic Cells.Stem Cell Reports (2016).

Aug 18:

Dobin, Alexander, Carrie A. Davis, Felix Schlesinger, Jorg Drenkow, Chris Zaleski, Sonali Jha, Philippe Batut, Mark Chaisson, and Thomas R. Gingeras. “STAR: ultrafast universal RNA-seq aligner.Bioinformatics 29, no. 1 (2013): 15-21.

Aug 19:

Muniz, João RC, Kunde Guo, Nadia J. Kershaw, Vikram Ayinampudi, Frank von Delft, Jeffrey J. Babon, and Alex N. Bullock. “Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.Journal of molecular biology 425, no. 17 (2013): 3166-3177.

Aug 20:

Guillerey, Camille, Nicholas D. Huntington, and Mark J. Smyth. “Targeting natural killer cells in cancer immunotherapy.Nature Immunology 17, no. 9 (2016): 1025-1036.

Aug 21:

Masuda, Kazuya, and Tadamitsu Kishimoto. “CD5: A New Partner for IL-6.” Immunity 44, no. 4 (2016): 720-722.

Aug 22:

Moss-Racusin, Corinne A., Jojanneke van der Toorn, John F. Dovidio, Victoria L. Brescoll, Mark J. Graham, and Jo Handelsman. “A “Scientific Diversity” Intervention to Reduce Gender Bias in a Sample of Life Scientists.CBE-Life Sciences Education 15, no. 3 (2016): ar29.

Aug 23:

Obenauer, John C., Lewis C. Cantley, and Michael B. Yaffe. “Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs.Nucleic acids research 31, no. 13 (2003): 3635-3641.

Aug 24:

Chen, Chang-Zheng, Ling Li, Harvey F. Lodish, and David P. Bartel. “MicroRNAs modulate hematopoietic lineage 303, no. 5654 (2004): 83-86.

Aug 25:

Mueckler, Mike, Carla Caruso, Stephen A. Baldwin, Maria Panico, Ian Blench, Howard R. Morris, W. Jeffrey Allard, Gustav E. Lienhard, and Harvey F. Lodish. “Sequence and structure of a human glucose transporter.Science 229, no. 4717 (1985): 941-945.

Aug 26:

Lodish, Harvey F. “Accommodating family life: mentoring future female faculty members.Trends in cell biology 25, no. 3 (2015): 109-111.

Aug 27:

de Koning-Ward, Tania F., Paul R. Gilson, and Brendan S. Crabb. “Advances in molecular genetic systems in malaria.” Nature Reviews Microbiology 13, no. 6 (2015): 373-387.

Aug 28:

Koonin, Eugene V., and Mart Krupovic. “Evolution of adaptive immunity from transposable elements combined with innate immune systems.” Nature Reviews Genetics 16, no. 3 (2015): 184-192.

Aug 29:

Sulonen, Anna-Maija, Pekka Ellonen, Henrikki Almusa, Maija Lepistö, Samuli Eldfors, Sari Hannula, Timo Miettinen et al. “Comparison of solution-based exome capture methods for next generation sequencing.” Genome biology 12, no. 9 (2011): 1.

Aug 30:

Hodge, David R., Elaine M. Hurt, and William L. Farrar. “The role of IL-6 and STAT3 in inflammation and cancer.” European journal of cancer 41, no. 16 (2005): 2502-2512.

Aug 31:

Shuai, Ke, and Bin Liu. “Regulation of JAK–STAT signalling in the immune system.Nature Reviews Immunology 3, no. 11 (2003): 900-911.


July: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter. Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.


July 1:

Wilson, Christopher GM, Thomas J. Magliery, and Lynne Regan. “Detecting protein-protein interactions with GFP-fragment reassembly.Nature methods 1, no. 3 (2004): 255-262.

July 2:

Gerlier, Denis, and Nicole Thomasset. “Use of MTT colorimetric assay to measure cell activation.Journal of immunological methods 94, no. 1-2 (1986): 57-63.

July 3:

Quail, Michael A., Iwanka Kozarewa, Frances Smith, Aylwyn Scally, Philip J. Stephens, Richard Durbin, Harold Swerdlow, and Daniel J. Turner. “A large genome center’s improvements to the Illumina sequencing system.Nature methods 5, no. 12 (2008): 1005-1010.

July 4:

Bonnici, Vincenzo, and Vincenzo Manca. “Informational laws of genome structures.Scientific Reports 6 (2016): 28840.

July 5:

Wang, J., E. Santiago, and A. Caballero. “Prediction and estimation of effective population size.Heredity (2016).

July 6:

Zhou, Honglin, Min Xu, Qian Huang, Adam T. Gates, Xiaohua D. Zhang, John C. Castle, Erica Stec et al. “Genome-scale RNAi screen for host factors required for HIV replication.” Cell host & microbe 4, no. 5 (2008): 495-504.

July 7:

Luo, Ji, Michael J. Emanuele, Danan Li, Chad J. Creighton, Michael R. Schlabach, Thomas F. Westbrook, Kwok-Kin Wong, and Stephen J. Elledge. “A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.” Cell 137, no. 5 (2009): 835-848.

July 8:

Mohseni, Morvarid, Jianlong Sun, Allison Lau, Stephen Curtis, Jeffrey Goldsmith, Victor L. Fox, Chongjuan Wei et al. “A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway.” Nature cell biology 16, no. 1 (2014): 108-117.

July 9:

Hoi, Charlene SL, Wenjun Xiong, and Ilaria Rebay. “Retinal Axon Guidance Requires Integration of Eya and the JAK/STAT Pathway into Phosphotyrosine-Based Signaling Circuitries in Drosophila.” Genetics (2016): genetics-115.

July 10:

Stark, George R., and James E. Darnell. “The JAK-STAT pathway at twenty.” Immunity 36, no. 4 (2012): 503-514.

July 11:

Thorvaldsdóttir, Helga, James T. Robinson, and Jill P. Mesirov. “Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration.” Briefings in bioinformatics 14, no. 2 (2013): 178-192.

July 12:

Krzywinski, Martin, Jacqueline Schein, Inanc Birol, Joseph Connors, Randy Gascoyne, Doug Horsman, Steven J. Jones, and Marco A. Marra. “Circos: an information aesthetic for comparative genomics.Genome research 19, no. 9 (2009): 1639-1645.

July 13:

Marguerat, Samuel, and Jürg Bähler. “RNA-seq: from technology to biology.” Cellular and molecular life sciences 67, no. 4 (2010): 569-579.

July 14:

Cirulli, Elizabeth T., Brittany N. Lasseigne, Slavé Petrovski, Peter C. Sapp, Patrick A. Dion, Claire S. Leblond, Julien Couthouis et al. “Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways.Science 347, no. 6229 (2015): 1436-1441.

July 15:

Loman, Nicholas J., and Mick Watson. “Successful test launch for nanopore sequencing.” Nature methods 12, no. 4 (2015): 303-304.

July 16:

Robert, Christelle, and Mick Watson. “Errors in RNA-Seq quantification affect genes of relevance to human disease.Genome biology 16, no. 1 (2015): 1.

July 17:

Uyeda, Josef C., Daniel S. Caetano, and Matthew W. Pennell. “Comparative analysis of principal components can be misleading.Systematic biology (2015): syv019.

July 18:

Sakakibara, Daisuke, Atsuko Sasaki, Teppei Ikeya, Junpei Hamatsu, Tomomi Hanashima, Masaki Mishima, Masatoshi Yoshimasu et al. “Protein structure determination in living cells by in-cell NMR spectroscopy.Nature 458, no. 7234 (2009): 102-105

July 19:

Law, Charity W., Yunshun Chen, Wei Shi, and Gordon K. Smyth. “Voom: precision weights unlock linear model analysis tools for RNA-seq read counts.Genome biology 15, no. 2 (2014): 1.

July 20:

Shalem, Ophir, Neville E. Sanjana, and Feng Zhang. “High-throughput functional genomics using CRISPR-Cas9.” Nature Reviews Genetics 16, no. 5 (2015): 299-311.

July 21:

Jones, Bryony. “Chromosome biology: Diverse evolution of sex chromosomes in flies.Nature Reviews Genetics 16, no. 6 (2015): 316-317.

July 22:

Wright, Jason B., and Neville E. Sanjana. “CRISPR Screens to Discover Functional Noncoding Elements.Trends in Genetics (2016)

July 23:

Trenker, R., M. J. Call, and M. E. Call. “Progress and prospects for structural studies of transmembrane interactions in single-spanning receptors.” Current opinion in structural biology 39 (2016): 115.

July 24:

Lee, Michael J., and Michael B. Yaffe. “Protein regulation in signal transduction.” Cold Spring Harbor perspectives in biology 8, no. 6 (2016): a005918.

July 25:

Yaffe, Michael B. “How to “cell” a genomic or proteomic screen.” Science signaling 1, no. 47 (2008): eg9-eg9.

July 26:

Yaffe, Michael B., and Nancy R. Gough. “Leveraging signaling research to understand and treat disease.Sci. Signal. 9, no. 421 (2016): eg4-eg4.

July 27:

Roberts, Kathryn G., Yongjin Li, Debbie Payne-Turner, Richard C. Harvey, Yung-Li Yang, Deqing Pei, Kelly McCastlain et al. “Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.New England journal of medicine 371, no. 11 (2014): 1005-1015.

July 28:

Zhang, Xiaotian, Jianzhong Su, Mira Jeong, Myunggon Ko, Yun Huang, Hyun Jung Park, Anna Guzman et al. “DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.Nature Genetics (2016).

July 29:

Weinstein, John N., Eric A. Collisson, Gordon B. Mills, Kenna R. Mills Shaw, Brad A. Ozenberger, Kyle Ellrott, Ilya Shmulevich, Chris Sander, Joshua M. Stuart, and Cancer Genome Atlas Research Network. “The cancer genome atlas pan-cancer analysis project.Nature genetics 45, no. 10 (2013): 1113-1120.

July 30:

Lawrence, Michael S., Petar Stojanov, Paz Polak, Gregory V. Kryukov, Kristian Cibulskis, Andrey Sivachenko, Scott L. Carter et al. “Mutational heterogeneity in cancer and the search for new cancer-associated genes.Nature 499, no. 7457 (2013): 214-218.

July 31:

Wright, Peter E., and H. Jane Dyson. “Intrinsically disordered proteins in cellular signalling and regulation.Nature Reviews Molecular Cell Biology 16, no. 1 (2015): 18-29.

June: 366 papers in 2016


As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter. Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.


June 1:

Gordon, Siamon. “Pattern recognition receptors: doubling up for the innate immune response.Cell 111, no. 7 (2002): 927-930.

June 2:

Kirkpatrick, Mark. “Sexual selection and the evolution of female choice.” Evolution (1982): 1-12.

June 3:

Dobzhansky, Theodosius. “Nothing in biology makes sense except in the light of evolution.” The american biology teacher 75, no. 2 (2013): 87-91.

June 4:

Barrios-Rodiles, Miriam, Kevin R. Brown, Barish Ozdamar, Rohit Bose, Zhong Liu, Robert S. Donovan, Fukiko Shinjo et al. “High-throughput mapping of a dynamic signaling network in mammalian cells.” Science 307, no. 5715 (2005): 1621-1625.

June 5:

Wittig, Ilka, Hans-Peter Braun, and Hermann Schägger. “Blue native PAGE.” Nature Protocols 1 (2006): 418-428.

June 6:

Evason, Kimberley J., Macrina T. Francisco, Vladislava Juric, Sanjeev Balakrishnan, Maria del Pilar Lopez Pazmino, John D. Gordan, Sanjay Kakar, Jan Spitsbergen, Andrei Goga, and Didier YR Stainier. “Identification of chemical inhibitors of β-catenin-driven liver tumorigenesis in zebrafish.PLoS Genet 11, no. 7 (2015): e1005305.

June 7, 8, 9, 10 and 11 (Sorry, but it is really long):

Darlington, Cyril Dean. “The evolution of genetic systems.The Evolution of Genetic Systems. (1939).

June 12:

Akira, S. H. I. Z. U. O., T. O. S. H. I. O. Hirano, T. E. T. S. U. Y. A. Taga, and T. A. D. A. M. I. T. S. U. Kishimoto. “Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF).The FASEB journal 4, no. 11 (1990): 2860-2867.

June 13:

Kishimoto, Tadamitsu, Shizuo Akira, Masashi Narazaki, and Tetsuya Taga. “Interleukin-6 family of cytokines and gp130.Blood 86, no. 4 (1995): 1243-1254.

June 14:

Alexander, Warren S., and Douglas J. Hilton. “The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response.Annu. Rev. Immunol. 22 (2004): 503-529.

June 15:

Brouwer, Jason M., Dana Westphal, Grant Dewson, Adeline Y. Robin, Rachel T. Uren, Ray Bartolo, Geoff V. Thompson, Peter M. Colman, Ruth M. Kluck, and Peter E. Czabotar. “Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.Molecular cell 55, no. 6 (2014): 938-946.

June 16:

Stafford, C. A., and U. Nachbur. “A NODding acquaintance with ER stress.” Cell Death Discovery 2 (2016).

June 17:

Nachbur, Ueli, Che A. Stafford, Aleksandra Bankovacki, Yifan Zhan, Lisa M. Lindqvist, Berthe K. Fiil, Yelena Khakham et al. “A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production.” Nature communications 6 (2015).

June 18:

Sheridan, Julie M., Matthew E. Ritchie, Sarah A. Best, Kun Jiang, Tamara J. Beck, François Vaillant, Kevin Liu et al. “A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.” BMC cancer 15, no. 1 (2015): 1.

June 19:

Alberts, Bruce. “On becoming a scientist.Science 326, no. 5955 (2009): 916-916.

June 20:

Witkowski, M. T., L. Cimmino, Y. Hu, T. Trimarchi, H. Tagoh, M. D. McKenzie, S. A. Best et al. “Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.” Leukemia 29, no. 6 (2015): 1301-1311.

June 21:

Wainer, Howard. “How to display data badly.” The American Statistician 38, no. 2 (1984): 137-147.

June 22:

DasGupta, Ramanuj, Ajamete Kaykas, Randall T. Moon, and Norbert Perrimon. “Functional genomic analysis of the Wnt-wingless signaling pathway.” Science 308, no. 5723 (2005): 826-833.

June 23:

Wang, Huayi, Liming Sun, Lijing Su, Josep Rizo, Lei Liu, Li-Feng Wang, Fu-Sheng Wang, and Xiaodong Wang. “Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.Molecular cell 54, no. 1 (2014): 133-146.

June 24:

Croker, Ben A., Danielle L. Krebs, Jian-Guo Zhang, Sam Wormald, Tracy A. Willson, Edouard G. Stanley, Lorraine Robb et al. “SOCS3 negatively regulates IL-6 signaling in vivo.” Nature immunology 4, no. 6 (2003): 540-545.

June 25:

Pinker, Steven, Martin A. Nowak, and James J. Lee. “The logic of indirect speech.Proceedings of the National Academy of sciences 105, no. 3 (2008): 833-838.

June 26:

Bergamin, Elisa, Jinhua Wu, and Stevan R. Hubbard. “Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.Structure 14, no. 8 (2006): 1285-1292.

June 27:

Pinker, Steven, and Paul Bloom. “Natural language and natural selection.” Behavioral and brain sciences 13, no. 04 (1990): 707-727.

June 28:

Ramirez, Steve, Xu Liu, Pei-Ann Lin, Junghyup Suh, Michele Pignatelli, Roger L. Redondo, Tomás J. Ryan, and Susumu Tonegawa. “Creating a false memory in the hippocampus.” Science 341, no. 6144 (2013): 387-391.

June 29:

Wu, Chung-I., Norman A. Johnson, and Michael F. Palopoli. “Haldane’s rule and its legacy: Why are there so many sterile males?.Trends in Ecology & Evolution 11, no. 7 (1996): 281-284.

June 30:

Hershey, A. D., June Dixon, and Martha Chase. “NUCLEIC ACID ECONOMY IN BACTERIA INFECTED WITH BACTERIOPHAGE T2 I. PURINE AND PYRIMIDINE COMPOSITION.” The Journal of general physiology 36, no. 6 (1953): 777-789.

May: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter. Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.

May 1:

Letunic, Ivica, and Peer Bork. “Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation.Bioinformatics 23, no. 1 (2007): 127-128.

May 2:

Skiniotis, Georgios, Martin J. Boulanger, K. Christopher Garcia, and Thomas Walz. “Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor.” Nature structural & molecular biology 12, no. 6 (2005): 545-551.

May 3:

Cuff, James A., Michele E. Clamp, Asim S. Siddiqui, Matt Finlay, and Geoffrey J. Barton. “JPred: a consensus secondary structure prediction server.Bioinformatics 14, no. 10 (1998): 892-893.

May 4:

Ozaki, Katsutoshi, and Warren J. Leonard. “Cytokine and cytokine receptor pleiotropy and redundancy.Journal of Biological Chemistry 277, no. 33 (2002): 29355-29358.

May 5:

Cuff, James A., Michele E. Clamp, Asim S. Siddiqui, Matt Finlay, and Geoffrey J. Barton. “JPred: a consensus secondary structure prediction server.Bioinformatics 14, no. 10 (1998): 892-893.

May 6:

Lim, Megan SC, Margaret E. Hellard, and Campbell K. Aitken. “The case of the disappearing teaspoons: longitudinal cohort study of the displacement of teaspoons in an Australian research institute.BMJ 331, no. 7531 (2005): 1498-1500.

May 7: 

Jenkins, Misty R., and Gillian M. Griffiths. “The synapse and cytolytic machinery of cytotoxic T cells.Current opinion in immunology 22, no. 3 (2010): 308-313.

May 8:

Hilton, Douglas J., Stephanie S. Watowich, Luba Katz, and Harvey F. Lodish. “Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor.” Journal of Biological Chemistry 271, no. 9 (1996): 4699-4708.

May 9:

Gargiulo, Gaetano, Michela Serresi, Matteo Cesaroni, Danielle Hulsman, and Maarten van Lohuizen. “In vivo shRNA screens in solid tumors.” Nature protocols 9, no. 12 (2014): 2880-2902.

May 10:

Simon, Michael A., David DL Bowtell, G. Steven Dodson, Todd R. Laverty, and Gerald M. Rubin. “Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.Cell 67, no. 4 (1991): 701-716.

May 11:

Kile, Benjamin T., and Douglas J. Hilton. “The art and design of genetic screens: mouse.Nature Reviews Genetics 6, no. 7 (2005): 557-567.

May 12:

St Johnston, Daniel. “The art and design of genetic screens: Drosophila melanogaster.” Nature reviews genetics 3, no. 3 (2002): 176-188.

May 13:

Patton, E. Elizabeth, and Leonard I. Zon. “The art and design of genetic screens: zebrafish.Nature Reviews Genetics 2, no. 12 (2001): 956-966.

May 14:

Boutros, Michael, and Julie Ahringer. “The art and design of genetic screens: RNA interference.Nature Reviews Genetics 9, no. 7 (2008): 554-566.

May 15:

Kunst, Michael, Matthew CF Tso, D. Dipon Ghosh, Erik D. Herzog, and Michael N. Nitabach. “Rhythmic control of activity and sleep by class B1 GPCRs.Critical reviews in biochemistry and molecular biology 50, no. 1 (2015): 18-30.

May 16:

Grimm, Stefan. “The art and design of genetic screens: mammalian culture cells.” Nature Reviews Genetics 5, no. 3 (2004): 179-189.

may 17:

Forsburg, Susan L. “The art and design of genetic screens: yeast.” Nature Reviews Genetics 2, no. 9 (2001): 659-668.

May 18:

Goodwin, Sara, John D. McPherson, and W. Richard McCombie. “Coming of age: ten years of next-generation sequencing technologies.Nature Reviews Genetics 17, no. 6 (2016): 333-351.

May 19:

Zhang, Chunyan, Hong Xin, Wang Zhang, Paul J. Yazaki, Zhifang Zhang, Keith Le, Wenzhao Li et al. “CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.Immunity 44, no. 4 (2016): 913-923.

May 20:

Loman, Nick, and Mick Watson. “So you want to be a computational biologist?.” Nature biotechnology 31, no. 11 (2013): 996-998.

May 21:

Dranoff, Glenn. “Cytokines in cancer pathogenesis and cancer therapy.” Nature Reviews Cancer 4, no. 1 (2004): 11-22.

May 22:

Hilton, Douglas J., Rachael T. Richardson, Warren S. Alexander, Elizabeth M. Viney, Tracy A. Willson, Naomi S. Sprigg, Robyn Starr, Sandra E. Nicholson, Donald Metcalf, and Nicos A. Nicola. “Twenty proteins containing a C-terminal SOCS box form five structural classes.Proceedings of the National Academy of Sciences 95, no. 1 (1998): 114-119.

May 23:

Tjio, Joe Hin, and Theodore T. Puck. “Genetics of somatic mammalian cells: II. Chromosomal constitution of cells in tissue culture.” The Journal of experimental medicine 108, no. 2 (1958): 259.

May 24:

Kao, Fa‐Ten, and Theodore T. Puck. “Genetics of somatic mammalian cells. IX. Quantitation of mutagenesis by physical and chemical agents.” Journal of cellular physiology 74, no. 3 (1969): 245-257.

May 25:

Wang, Zimou, Weiliang Xu, Lei Liu, and Ting F. Zhu. “A synthetic molecular system capable of mirror-image genetic replication and transcription.” Nature Chemistry (2016).

May 26:

Paddison, Patrick J., and Gregory J. Hannon. “RNA interference: the new somatic cell genetics?.Cancer cell 2, no. 1 (2002): 17-23.

May 27:

Stankowski, Leon F., Kenneth R. Tindall, and Abraham W. Hsie. “Quantitative and molecular analyses of ethyl methanesulfonate-and ICR 191-induced mutation in AS52 cells.Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 160, no. 2 (1986): 133-147.

May 28:

Simpson, Richard J., Annet Hammacher, David K. Smith, Jacqueline M. Matthews, and Larry D. Ward. “Interleukin‐6: Structure‐function relationships.Protein Science 6, no. 5 (1997): 929-955.

May 29:

Paonessa, Giacomo, Rita Graziani, Anna De Serio, Rocco Savino, Laura Ciapponi, Armin Lahm, Anna Laura Salvati, Carlo Toniatti, and Gennaro Ciliberto. “Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling.” The EMBO Journal 14, no. 9 (1995): 1942.

May 30:

Hsin, Jing-Ping, Wencheng Li, Mainul Hoque, Bin Tian, and James L. Manley. “RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells.” ELife 3 (2014): e02112.

May 31:

Dobzhansky, Theodosius. “Nothing in biology makes sense except in the light of evolution.” The american biology teacher 75, no. 2 (2013): 87-91.




April: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter. Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.

April 1:

Majewski, Ian J., Matthew E. Ritchie, Belinda Phipson, Jason Corbin, Miha Pakusch, Anja Ebert, Meinrad Busslinger et al. “Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.Blood 116, no. 5 (2010): 731-739.

April 2:

Dunn, Timothy W., Yu Mu, Sujatha Narayan, Owen Randlett, Eva A. Naumann, Chao-Tsung Yang, Alexander F. Schier, Jeremy Freeman, Florian Engert, and Misha B. Ahrens. “Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion.eLife 5 (2016): e12741.

April 3:

Chowdhury, Saikat, and Ram Rup Sarkar. “Comparison of human cell signaling pathway databases—evolution, drawbacks and challenges.Database 2015 (2015): bau126.

April 4:

Janes, Kevin A., H. Christian Reinhardt, and Michael B. Yaffe. “Cytokine-induced signaling networks prioritize dynamic range over signal strength.” Cell 135, no. 2 (2008): 343-354.

April 5:

Coyle, Scott, and Wendell A. Lim. “Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution.” eLife (2016): e12435.

April 6:

Wang, Zhong, Mark Gerstein, and Michael Snyder. “RNA-Seq: a revolutionary tool for transcriptomics.” Nature Reviews Genetics 10, no. 1 (2009): 57-63.

April 7:

Manning, Gerard, Gregory D. Plowman, Tony Hunter, and Sucha Sudarsanam. “Evolution of protein kinase signaling from yeast to man.Trends in biochemical sciences 27, no. 10 (2002): 514-520.

April 8:

Whitney, Mike, Edward Rockenstein, Greg Cantin, Tom Knapp, Gregor Zlokarnik, Pam Sanders, Kyle Durick, Frank F. Craig, and Paul A. Negulescu. “A genome-wide functional assay of signal transduction in living mammalian cells.Nature biotechnology 16, no. 13 (1998): 1329-1333.

April 9:

Bogdanović, Ozren, Arne H. Smits, Elisa de la Calle Mustienes, Juan J. Tena, Ethan Ford, Ruth Williams, Upeka Senanayake et al. “Active DNA demethylation at enhancers during the vertebrate phylotypic period.Nature genetics (2016).

April 10:

Grewal, Savraj S. “Why should cancer biologists care about tRNAs? tRNA synthesis, mRNA translation and the control of growth.” Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849, no. 7 (2015): 898-907.

April 11:

Chen, Kelan, Renwick CJ Dobson, Isabelle Lucet, Samuel N. Young, Frederick G. Pearce, Marnie E. Blewitt, and James M. Murphy. “The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.Biochemical Journal (2016): BCJ20160189.

April 12:

Gilbert, Luke A., Matthew H. Larson, Leonardo Morsut, Zairan Liu, Gloria A. Brar, Sandra E. Torres, Noam Stern-Ginossar et al. “CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.” Cell 154, no. 2 (2013): 442-451.

April 13:

Smith, Donald B., and Kevin S. Johnson. “Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.” Gene 67, no. 1 (1988): 31-40.

April 14:

Miton, Charlotte M., and Nobuhiko Tokuriki. “How mutational epistasis impairs predictability in protein evolution and design.” Protein Science (2016).

April 15:

Jadwin, Joshua A., Dongmyung Oh, Timothy G. Curran, Mari Ogiue-Ikeda, Lin Jia, Forest M. White, Kazuya Machida, Ji Yu, and Bruce J. Mayer. “Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases.” eLife 5 (2016): e11835.

April 16:

Fraser, Nicholas J., Jian-Wei Liu, Peter D. Mabbitt, Galen J. Correy, Chris W. Coppin, Mathilde Lethier, Matthew A. Perugini et al. “Evolution of Protein Quaternary Structure in Response to Selective Pressure for Increased Thermostability.Journal of Molecular Biology (2016).

April 17:

Jeggo, Penny A., Laurence H. Pearl, and Antony M. Carr. “DNA repair, genome stability and cancer: a historical perspective.” Nature Reviews Cancer 16, no. 1 (2016): 35-42.

April 18:

Croker, Ben A., Hiu Kiu, Marc Pellegrini, Jesse Toe, Simon Preston, Donald Metcalf, Joanne A. O’Donnell et al. “IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3.Immunology and cell biology 90, no. 1 (2012): 124-129.

April 19:

Chen, Sidi, Neville E. Sanjana, Kaijie Zheng, Ophir Shalem, Kyungheon Lee, Xi Shi, David A. Scott et al. “Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.Cell 160, no. 6 (2015): 1246-1260.

April 20:

Müller-Newen, Gerhard. “The cytokine receptor gp130: faithfully promiscuous.” Science Signaling 2003, no. 201 (2003): pe40-pe40.

April 21:

Greaney, Marie R., Ann E. Privorotskiy, Kristen P. D’Elia, and David Schoppik. “Ocular Motoneuron Pools Develop Along a Dorsoventral Axis in Zebrafish, Danio rerio.” bioRxiv (2016): 049296.

April 22:

Liongue, Clifford, Tarannum Taznin, and Alister C. Ward. “Signaling via the CytoR/JAK/STAT/SOCS pathway: Emergence during evolution.Molecular immunology 71 (2016): 166-175.

April 23:

Tiwari, Ravi P., Wayne G. Reeve, Michael J. Dilworth, and Andrew R. Glenn. “Acid tolerance in Rhizobium meliloti strain WSM419 involves a two-component sensor-regulator system.Microbiology 142, no. 7 (1996): 1693-1704.

April 24:

Lopresti, Adrian L., Michael Maes, Garth L. Maker, Sean D. Hood, and Peter D. Drummond. “Curcumin for the treatment of major depression: a randomised, double-blind, placebo controlled study.Journal of affective disorders 167 (2014): 368-375.

April 25:

Boulanger, Martin J., Dar-chone Chow, Elena Brevnova, Monika Martick, Gordon Sandford, John Nicholas, and K. Christopher Garcia. “Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6.” Journal of molecular biology 335, no. 2 (2004): 641-654.

April 26:

Cong, Le, F. Ann Ran, David Cox, Shuailiang Lin, Robert Barretto, Naomi Habib, Patrick D. Hsu et al. “Multiplex genome engineering using CRISPR/Cas systems.” Science 339, no. 6121 (2013): 819-823.

April 27:

Branton, Daniel, David W. Deamer, Andre Marziali, Hagan Bayley, Steven A. Benner, Thomas Butler, Massimiliano Di Ventra et al. “The potential and challenges of nanopore sequencing.Nature biotechnology 26, no. 10 (2008): 1146-1153.

April 28:

Gouy, Manolo, Stéphane Guindon, and Olivier Gascuel. “SeaView version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building.Molecular biology and evolution 27, no. 2 (2010): 221-224.

April 29:

Kishimoto, Tadamitsu, Shizuo Akira, Masashi Narazaki, and Tetsuya Taga. “Interleukin-6 family of cytokines and gp130.Blood 86, no. 4 (1995): 1243-1254.

April 30:

Letunic, Ivica, and Peer Bork. “Interactive Tree Of Life (iTOL): an online tool for phylogenetic tree display and annotation.” Bioinformatics 23, no. 1 (2007): 127-128.

March: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter.

Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.

March 1:

Grimes, David Robert. “Proposed mechanisms for homeopathy are physically impossible.” Focus on Alternative and Complementary Therapies 17, no. 3 (2012): 149-155.

March 2:

Booker, Tom, Rob W. Ness, and Deborah Charlesworth. “Molecular Evolution: Breakthroughs and Mysteries in Batesian Mimicry.Current Biology 25, no. 12 (2015): R506-R508.

March 3:

Kristensen, Niels P., Douglas J. Hilton, Axel Kallies, Liz Milla, Jadranka Rota, Niklas Wahlberg, Stephen A. Wilcox et al. “A new extant family of primitive moths from Kangaroo Island, Australia, and its significance for understanding early Lepidoptera evolution.Systematic Entomology 40, no. 1 (2015): 5-16.

March 4:

Coyne, Jerry A. “The genetic basis of Haldane’s rule.” Nature 314, no. 6013 (1984): 736-738.

March 5:

Trenker, Raphael, Matthew E. Call, and Melissa J. Call. “Crystal Structure of the Glycophorin A Transmembrane Dimer in Lipidic Cubic Phase.” Journal of the American Chemical Society 137, no. 50 (2015): 15676-15679.

March 6:

Chen, Sidi, Neville E. Sanjana, Kaijie Zheng, Ophir Shalem, Kyungheon Lee, Xi Shi, David A. Scott et al. “Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.” Cell 160, no. 6 (2015): 1246-1260.

March 7:

Tai, Andrew W., Yair Benita, Lee F. Peng, Sun-Suk Kim, Naoya Sakamoto, Ramnik J. Xavier, and Raymond T. Chung. “A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.Cell host & microbe 5, no. 3 (2009): 298.

March 8:

Shalem, Ophir, Neville E. Sanjana, Ella Hartenian, Xi Shi, David A. Scott, Tarjei S. Mikkelsen, Dirk Heckl et al. “Genome-scale CRISPR-Cas9 knockout screening in human cells.Science 343, no. 6166 (2014): 84-87.

March 9:

Zhou, Yuexin, Shiyou Zhu, Changzu Cai, Pengfei Yuan, Chunmei Li, Yanyi Huang, and Wensheng Wei. “High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells.” Nature 509, no. 7501 (2014): 487-491.

March 10:

Crick, Francis HC, and James D. Watson. “The complementary structure of deoxyribonucleic acid.” In Proceedings of the Royal Society of London A: Mathematical, Physical and Engineering Sciences, vol. 223, no. 1152, pp. 80-96. The Royal Society, 1954.

March 11:

Domazet-Lošo, Tomislav, and Diethard Tautz. “A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns.” Nature 468, no. 7325 (2010): 815-818.

March 12:

Koonin, Eugene V. “Comparative genomics, minimal gene-sets and the last universal common ancestor.Nature Reviews Microbiology 1, no. 2 (2003): 127-136.

March 13:

Ciccarelli, Francesca D., Tobias Doerks, Christian Von Mering, Christopher J. Creevey, Berend Snel, and Peer Bork. “Toward automatic reconstruction of a highly resolved tree of 311, no. 5765 (2006): 1283-1287.

March 14:

Krebs, H. A., R. N. Speake, and R. Hems. “Acceleration of renal gluconeogenesis by ketone bodies and fatty acids.Biochemical Journal 94, no. 3 (1965): 712.

March 15:

Lespinet, Olivier, Yuri I. Wolf, Eugene V. Koonin, and L. Aravind. “The role of lineage-specific gene family expansion in the evolution of eukaryotes.” Genome research 12, no. 7 (2002): 1048-1059.

March 16:

Ku, Chuan, Shijulal Nelson-Sathi, Mayo Roettger, Filipa L. Sousa, Peter J. Lockhart, David Bryant, Einat Hazkani-Covo, James O. McInerney, Giddy Landan, and William F. Martin. “Endosymbiotic origin and differential loss of eukaryotic genes.” Nature 524, no. 7566 (2015): 427-432.

March 17:

Ritchie, Matthew E., Belinda Phipson, Di Wu, Yifang Hu, Charity W. Law, Wei Shi, and Gordon K. Smyth. “limma powers differential expression analyses for RNA-sequencing and microarray studies.Nucleic acids research (2015): gkv007.

March 18:

Horlbeck, Max A., Lea B. Witkowsky, Benjamin Guglielmi, Joseph M. Replogle, Luke A. Gilbert, Jacqueline E. Villalta, Sharon E. Torigoe, Robert Tijan, and Jonathan S. Weissman. “Nucleosomes impede Cas9 access to DNA in vivo and in vitro.eLife 5 (2016): e12677.

March 19:

Supple, Megan A., Riccardo Papa, Heather M. Hines, W. Owen McMillan, and Brian A. Counterman. “Divergence with gene flow across a speciation continuum of Heliconius butterflies.BMC evolutionary biology 15, no. 1 (2015): 204.

March 20:

Sork, Victoria L. “Gene flow and natural selection shape spatial patterns of genes in tree populations: implications for evolutionary processes and applications.Evolutionary Applications 9, no. 1 (2016): 291-310.

March 21:

Pishesha, Novalia, Prathapan Thiru, Jiahai Shi, Jennifer C. Eng, Vijay G. Sankaran, and Harvey F. Lodish. “Transcriptional divergence and conservation of human and mouse erythropoiesis.Proceedings of the National Academy of Sciences 111, no. 11 (2014): 4103-4108.

March 22:

Pires-daSilva, André, and Ralf J. Sommer. “The evolution of signalling pathways in animal development.” Nature Reviews Genetics 4, no. 1 (2003): 39-49.

March 23:

Vaux, David L. “Basic statistics in cell biology.Annual review of cell and developmental biology 30 (2014): 23-37.

March 24:

Lazcano, Antonio, and Stanley L. Miller. “The origin and early evolution of life: prebiotic chemistry, the pre-RNA world, and time.Cell 85, no. 6 (1996): 793-798.

March 25:

Iismaa, Tiina P., and John Shine. “G protein-coupled receptors.Current opinion in cell biology 4, no. 2 (1992): 195-202.

March 26:

Kershaw, Nadia J., James M. Murphy, Isabelle S. Lucet, Nicos A. Nicola, and Jeffrey J. Babon. “Regulation of Janus kinases by SOCS proteins.Biochemical Society Transactions 41, no. 4 (2013): 1042-1047.

March 27:

Vaux, David L. “Research methods: Know when your numbers are significant.Nature 492, no. 7428 (2012): 180-181.

March 28:

Berthelot, Camille, Frédéric Brunet, Domitille Chalopin, Amélie Juanchich, Maria Bernard, Benjamin Noël, Pascal Bento et al. “The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.Nature communications 5 (2014).

March 29:

Carey, Lucas B. “RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits.eLife 4 (2015): e09945.

March 30:

Eyers, Patrick A. “TRIBBLES: A Twist in the Pseudokinase Tail.Structure 23, no. 11 (2015): 1974-1976.

March 31:

Xu, Jian, Zhen Shao, Dan Li, Huafeng Xie, Woojin Kim, Jialiang Huang, Jordan E. Taylor et al. “Developmental control of polycomb subunit composition by GATA factors mediates a switch to non-canonical functions.Molecular cell 57, no. 2 (2015): 304-316.

Feb: 366 papers in 2016

As one of my 2016 scientific resolutions I will be reading one paper every day of the year and posting each here (hopefully) daily. Along with me, Natalie Matosin, Martin Engel and Lauren Drogos will also be doing the same and likewise posting each paper on their respective blogs. You can also follow the three of us and the others who are joining us using the tag #366papers on twitter.

Also find Dr Lauren Drogos here, Dr Natalie Matosin here and find Dr Martin Engel here.


Feb 1:

Sadownik, Jan W., Elio Mattia, Piotr Nowak, and Sijbren Otto. “Diversification of self-replicating molecules.Nature Chemistry (2016).

Feb 2:

Bernhardt, Harold S., and Wayne M. Patrick. “Genetic code evolution started with the incorporation of glycine, followed by other small hydrophilic amino acids.” Journal of molecular evolution 78, no. 6 (2014): 307-309.

Feb 3:

Tsai, Yu-Hsuan, Sebastian Essig, John R. James, Kathrin Lang, and Jason W. Chin. “Selective, rapid and optically switchable regulation of protein function in live mammalian cells.Nature chemistry 7, no. 7 (2015): 554.

Feb 4:

Posadzki, Paul, Leala Watson, and Edzard Ernst. “Contamination and adulteration of herbal medicinal products (HMPs): an overview of systematic reviews.” European journal of clinical pharmacology 69, no. 3 (2013): 295-307.

Feb 5:

Farasat, I., and H. M. Salis. “A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation.PLoS computational biology 12, no. 1 (2016): e1004724-e1004724.

Feb 6:

Freeland, Stephen J., Robin D. Knight, Laura F. Landweber, and Laurence D. Hurst. “Early fixation of an optimal genetic code.Molecular Biology and Evolution 17, no. 4 (2000): 511-518.

Feb 7:

Wilson, William C., Hue-Tran Hornig-Do, Francesco Bruni, Jeong Ho Chang, Alexis A. Jourdain, Jean-Claude Martinou, Maria Falkenberg et al. “A human mitochondrial poly (A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression.Human molecular genetics 23, no. 23 (2014): 6345-6355.

Feb 8:

Murphy, Andrew J., Michael J. Kraakman, Helene L. Kammoun, Dragana Dragoljevic, Man KS Lee, Kate E. Lawlor, John M. Wentworth et al. “IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.Cell metabolism 23, no. 1 (2016): 155-164.

Feb 9:

Feng, Justin, Benjamin W. Jester, Christine E. Tinberg, Daniel J. Mandell, Mauricio S. Antunes, Raj Chari, Kevin J. Morey et al. “A general strategy to construct small molecule biosensors in eukaryotes.eLife (2015): e10606.

Feb 10:

Anderson, Douglas P., Dustin S. Whitney, Victor Hanson-Smith, Arielle Woznica, William Campodonico-Burnett, Brian F. Volkman, Nicole King, Kenneth E. Prehoda, and Joseph W. Thornton. “Evolution of an ancient protein function involved in organized multicellularity in animals.” eLife 5 (2016): e10147.

Feb 11:

Floor, Stephen N., and Jennifer A. Doudna. “Tunable protein synthesis by transcript isoforms in human cells.eLife (2016): e10921.

Feb 12:

Curry, Fitz-Roy E. “Drug delivery: Redefining tumour vascular barriers.” Nature Nanotechnology (2016).

Feb 13:

Bonning, Bryony C., Narinder Pal, Sijun Liu, Zhaohui Wang, S. Sivakumar, Philip M. Dixon, Glenn F. King, and W. Allen Miller. “Toxin delivery by the coat protein of an aphid-vectored plant virus provides plant resistance to aphids.” Nature biotechnology 32, no. 1 (2014): 102-105.

Feb 14:

Albors, Aida Rodrigo, Akira Tazaki, Fabian Rost, Sergej Nowoshilow, Osvaldo Chara, and Elly M. Tanaka. “Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration.eLife (2015): e10230.

Feb 15:

Jin, Jin, Xiaoping Xie, Yichuan Xiao, Hongbo Hu, Qiang Zou, Xuhong Cheng, and Shao-Cong Sun. “Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid.Nature immunology (2016).

Feb 16:

Zhao, Jinghui, Gonzalo A. Garcia, and Alfred L. Goldberg. “Control of proteasomal proteolysis by mTOR.Nature 529, no. 7586 (2016): E1-E2.

Feb 17:

Liu, Zhihua, Jinwoo Lee, Scott Krummey, Wei Lu, Huaibin Cai, and Michael J. Lenardo. “The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease.” Nature immunology 12, no. 11 (2011): 1063-1070.

Feb 18:

Coghlan, Megan L., Garth Maker, Elly Crighton, James Haile, Dáithí C. Murray, Nicole E. White, Roger W. Byard et al. “Combined DNA, toxicological and heavy metal analyses provides an auditing toolkit to improve pharmacovigilance of traditional Chinese medicine (TCM).Scientific reports 5 (2015).

Feb 19:

Atsak, Piray, Friederike M. Guenzel, Deniz Kantar-Gok, Ioannis Zalachoras, Piraye Yargicoglu, Onno C. Meijer, Gina L. Quirarte, Oliver T. Wolf, Lars Schwabe, and Benno Roozendaal. “Glucocorticoids mediate stress-induced impairment of retrieval of stimulus− response memory.” Psychoneuroendocrinology (2016).

Feb 20:

Murphy, Andrew J., Nora Bijl, Laurent Yvan-Charvet, Carrie B. Welch, Neha Bhagwat, Adili Reheman, Yiming Wang et al. “Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.” Nature medicine 19, no. 5 (2013): 586-594.

Feb 21:

Champer, Jackson, Anna Buchman, and Omar S. Akbari. “Cheating evolution: engineering gene drives to manipulate the fate of wild populations.Nature Reviews Genetics 17, no. 3 (2016): 146-159.

Feb 22:

Lai, Andicus, Paloma M. Sato, and Sergio G. Peisajovich. “Evolution of Synthetic Signaling Scaffolds by Recombination of Modular Protein Domains.ACS synthetic biology 4, no. 6 (2015): 714-722.

Feb 23:

Bee, Thomas, Emma LK Ashley, Sorrel RB Bickley, Andrew Jarratt, Pik-Shan Li, Jackie Sloane-Stanley, Berthold Göttgens, and Marella FTR de Bruijn. “The mouse Runx1+ 23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters.Blood 113, no. 21 (2009): 5121-5124.

Feb 24:

Krebs, Danielle L., and Douglas J. Hilton. “SOCS proteins: negative regulators of cytokine signaling.Stem cells 19, no. 5 (2001): 378-387.

Feb 25:

Bardwell, Lee. “A walk-through of the yeast mating pheromone response pathway.Peptides 26, no. 2 (2005): 339-350.

Feb 26:

Zhang, Fan, Yang Li, Zhongshu Tang, Anil Kumar, Chunsik Lee, Liping Zhang, Chaoyong Zhu et al. “Proliferative and survival effects of PUMA promote angiogenesis.Cell reports 2, no. 5 (2012): 1272-1285.

Feb 27:

Scotti, Marina M., and Maurice S. Swanson. “RNA mis-splicing in disease.Nature Reviews Genetics 17, no. 1 (2016): 19-32.

Feb 28:

Streisinger, George, Yoshimi Okada, Joyce Emrich, Judith Newton, Akira Tsugita, Eric Terzaghi, and M. Inouye. “Frameshift mutations and the genetic code.” In Cold Spring Harbor Symposia on Quantitative Biology, vol. 31, pp. 77-84. Cold Spring Harbor Laboratory Press, 1966.